Drugs / rhDNAse
rhDNAse
Trials 3
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1/21 trial | ||||||
| Phase 1/2 | NCT03994380 | Feb 2020 → May 2022 | asthma | National Jewish Health | Completed | No outcome recorded |
| Phase 21 trial · 1 missed | ||||||
| Phase 2 | NCT00169962 | Jan 2004 → Sep 2006 | asthma | Northwell Health | Completed | Missed primary |
| Phase 41 trial · 1 met primary | ||||||
| Phase 4 | NCT00557089 | Jan 2008 → Jun 2009 | cystic fibrosis | The Hospital for Sick Children | Completed | Met primary |
News releases announcing trial results or a regulatory action · 1
| Date | Issuer | Release |
|---|---|---|
| 2014-04-07 | Xenetic Biosciences, Inc. | Results Xenetic Biosciences Announces Positive Phase 1 Clinical Data for PulmoXen(TM) for Treatment of Cystic Fibrosis xeneticbio.com ↗
Xenetic Biosciences, Inc. (OTCBB:XBIO), a biopharmaceutical company focused on developing next-generation biologic drugs and novel oncology therapeutics, today announced the positive results from its Phase I clinical trial of PulmoXen TM for the treatment of cystic fibrosis. |
All press releases naming this drug 1 release
| Date | Issuer | Release |
|---|---|---|
| 2014-04-07 | Xenetic Biosciences, Inc. | Xenetic Biosciences Announces Positive Phase 1 Clinical Data for PulmoXen(TM) for Treatment of Cystic Fibrosis xeneticbio.com ↗ |
Evidence & citations 6 cited values
Every value below carries the sentence it was read from. 4 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | rh-DNase | “use of nebulized rh-DNase for 4 weeks in patients with neutrophilic asthma.” NCT03994380 ↗ |
| Known as | pulmozyme | “rhDNAse (pulmozyme)” NCT00169962 ↗ |
| Known as | Recombinant human deoxyriboneuclease | “Recombinant human deoxyriboneuclease (rhDNase) has not been investigated in refractory asthma.” NCT03994380 ↗ |
| Known as | RhDNAse Inhalation Solution | “Drug: RhDNAse Inhalation Solution” NCT03994380 ↗ |
| Modality | Protein / enzyme biologic | “Recombinant human deoxyriboneuclease (rhDNase)” NCT03994380 ↗ |
| Route | Inhaled | “three nebulized rhDNAse treatment groups” PMID 22580235 ↗ May 2012 |