Drugs / TEDATIOXETINE
last change Apr 2009 re-read 2 minutes ago

TEDATIOXETINE

Small molecule targets ADRA1A, HTR2A, HTR2C, SLC6A2, SLC6A3, SLC6A4 via inhibition

Developed for
major depressive disorder
Investigated by
H. Lundbeck A/S

Trials 1 · a red edge is where a trial was stopped

20082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT00599911 Oct 2007 → Mar 2009 major depressive disorder H. Lundbeck A/S Completed No outcome recorded

Evidence & citations 15 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as TEDATIOXETINE ChEMBL registry synonym — accepted as the source's own label CHEMBL2104986
Known as LU AA 24530 HYDROBROMIDE ChEMBL registry synonym — accepted as the source's own label CHEMBL2104986
Known as Lu AA24530 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00599911
Known as Lu AA24530 (HBr) ChEMBL registry synonym — accepted as the source's own label CHEMBL2104986
Known as Tedatioxetina ChEMBL registry synonym — accepted as the source's own label CHEMBL2104986
Known as TEDATIOXETINE HYDROBROMIDE ChEMBL registry synonym — accepted as the source's own label CHEMBL2104986
Action Inhibit “Serotonin 2a (5-HT2a) receptor antagonist” CHEMBL2104986
5

“Serotonin 2c (5-HT2c) receptor antagonist” CHEMBL2104986

“Alpha-1a adrenergic receptor antagonist” CHEMBL2104986

“Norepinephrine transporter inhibitor” CHEMBL2104986

“Serotonin transporter inhibitor” CHEMBL2104986

“Dopamine transporter inhibitor” CHEMBL2104986

Modality Small molecule CHEMBL2104986
Route Oral “per oral, once daily for 6 weeks” NCT00599911
Target ADRA1A “Alpha-1a adrenergic receptor antagonist” CHEMBL2104986
Target HTR2A “Serotonin 2a (5-HT2a) receptor antagonist” CHEMBL2104986
Target HTR2C “Serotonin 2c (5-HT2c) receptor antagonist” CHEMBL2104986
Target SLC6A2 “Norepinephrine transporter inhibitor” CHEMBL2104986
Target SLC6A3 “Dopamine transporter inhibitor” CHEMBL2104986
Target SLC6A4 “Serotonin transporter inhibitor” CHEMBL2104986