Drugs / CYT003-QbG10
last change Feb 2013 re-read 3 minutes ago

CYT003-QbG10

also known as QbG10

Vaccine targets TLR9 via activation

Developed for
perennial allergic rhinitis · allergic asthma · allergic rhinitis · house allergic alveolitis
Investigated by
Cytos Biotechnology AG

Trials 6

20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT00652223 Mar → Nov 2005 allergic asthma, perennial allergic rhinitis Cytos Biotechnology AG Completed No outcome recorded
Phase 25 trials
Phase 2 NCT00890734 Apr 2009 → Apr 2010 allergic asthma Cytos Biotechnology AG Completed No outcome recorded
Phase 2 NCT00800332 Nov 2008 → Apr 2010 allergic rhinitis Cytos Biotechnology AG Completed No outcome recorded
Phase 2 NCT00575003 Dec 2007 → Mar 2009 perennial allergic rhinitis Cytos Biotechnology AG Completed No outcome recorded
Phase 2 NCT00574223 Nov 2007 → Mar 2009 perennial allergic rhinitis Cytos Biotechnology AG Completed No outcome recorded
Phase 2 NCT00574704 Sep 2006 → Mar 2008 house allergic alveolitis, perennial allergic rhinitis Cytos Biotechnology AG Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as CYT003-QbG10 “Immunomodulator CYT003-QbG10 in combination with commercial house dust mite extract as used for routine SIT” NCT00652223 ↗
5

NCT00574223 ↗

NCT00800332 ↗

NCT00574704 ↗

NCT00890734 ↗

NCT00575003 ↗

Known as QbG10 “QbG10 (bacteriophage Qbeta-derived virus-like particle with CpG-motif G10 inside), a novel Toll-like receptor 9 agonist packaged into virus-like particles, was designed to...” PMID 23384679 ↗ Feb 2013
Action Activate “a novel Toll-like receptor 9 agonist packaged into virus-like particles, was designed to stimulate the immune system toward a TH1-mediated protective response.” PMID 23384679 ↗ Feb 2013
Modality Vaccine “a vaccine against house dust mite and/or cat allergy” NCT00575003 ↗
Route Subcutaneous “subcutaneous injections at 8 visits” NCT00574223 ↗
Target TLR9 “a novel Toll-like receptor 9 agonist packaged into virus-like particles” PMID 23384679 ↗ Feb 2013