Drugs / Zelenectide pevedotin
Zelenectide pevedotin
Trials 5 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1/21 trial | ||||||
| Phase 1/2 | NCT04561362 | Jul 2020 → Mar 2026 overdue | hormone receptor-positive breast cancer, non-small cell lung carcinoma, ovarian neoplasm, triple-negative breast carcinoma +1 | BicycleTx Limited | Active not recruiting | No outcome recorded |
| Phase 24 trials | ||||||
| Phase 2 | NCT07681674 | Aug 2026 → May 2030 expected | cancer | BicycleTx Limited | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT06933329 | Jul 2025 → Aug 2028 expected | non-small cell lung carcinoma | BicycleTx Limited | Active not recruiting | No outcome recorded |
| Phase 2 | NCT06840483 | Mar 2025 → Jun 2028 expected | breast cancer | BicycleTx Limited | Active not recruiting | No outcome recorded |
| Phase 2 | NCT06225596 | Jan 2024 → Mar 2028 expected | urothelial carcinoma | BicycleTx Limited | Active not recruiting | No outcome recorded |
Evidence & citations 8 cited values
Every value below carries the sentence it was read from. 7 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | zelenectide pevedotin | “Zelenectide pevedotin (BT8009) is a Bicycle Drug Conjugate” PMID 41197088 ↗ Nov 2025 |
| Known as | BT8009 | “Zelenectide pevedotin (BT8009)” NCT06840483 ↗ |
| Known as | Zelenectida pevedotina | ChEMBL registry synonym — accepted as the source's own label CHEMBL5314903 ↗ |
| Known as | Zelenectide pavedotin | ChEMBL registry synonym — accepted as the source's own label CHEMBL5314903 ↗ |
| Known as | Zelenectide pevedotine | ChEMBL registry synonym — accepted as the source's own label CHEMBL5314903 ↗ |
| Modality | Peptide | “highly selective Nectin-4-targeting Bicycle peptide” PMID 41197088 ↗ Nov 2025 |
| Modality | Protein / enzyme biologic | — CHEMBL5314903 ↗ |
| Route | Intravenous | “received zelenectide pevedotin intravenously at 2.5, 5.0, or 7.5 mg/m2” PMID 41197088 ↗ Nov 2025 |