Drugs / GEDIVUMAB
last change Nov 2017 re-read 2 minutes ago

GEDIVUMAB

also known as MHAA4549A · RG7745 · RO6876802

Monoclonal antibody

Developed for
influenza
Investigated by
Genentech, Inc.

Trials 5 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT02284607 Nov 2014 → Mar 2015 Genentech, Inc. Completed No outcome recorded
Phase 1 NCT01877785 Jul → Nov 2013 Genentech, Inc. Completed No outcome recorded
Phase 23 trials
Phase 2 NCT02623322 Oct 2016 → Nov 2017 influenza Genentech, Inc. Completed No outcome recorded
Phase 2 NCT02293863 Jan 2015 → May 2017 influenza Genentech, Inc. Completed No outcome recorded
Phase 2 NCT01980966 Nov 2013 → Jun 2014 Genentech, Inc. Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as GEDIVUMAB ChEMBL registry synonym — accepted as the source's own label CHEMBL4298040
Known as MHAA4549A MHAA4549A, a human monoclonal antibody targeting the hemagglutinin stalk region of influenza A virus (IAV), is being developed as a therapeutic for patients hospitalized with...” PMID 28807912 Oct 2017
4

NCT02284607

NCT02623322

NCT01877785

NCT02293863

Known as RG7745 ChEMBL registry synonym — accepted as the source's own label CHEMBL4298040
Known as RO6876802 ChEMBL registry synonym — accepted as the source's own label CHEMBL4298040
Modality Monoclonal antibody “MHAA4549A is a human monoclonal immunoglobulin (Ig) G1 antibody” PMID 27381392 Aug 2016
Route Intravenous “single intravenous dose of 1.5, 5, 15, or 45 mg/kg MHAA4549A” PMID 27381392 Aug 2016