Drugs / CT7, MAGE-A3, and WT1 mRNA-electroporated Langerhans cells ( LCs)
last change Jun 2022 re-read 3 minutes ago

CT7, MAGE-A3, and WT1 mRNA-electroporated Langerhans cells ( LCs)

Cell therapy

Developed for
plasma cell myeloma
Investigated by
Memorial Sloan Kettering Cancer Center

Trials 1

20142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT01995708 Jan 2014 → Jun 2022 plasma cell myeloma Memorial Sloan Kettering Cancer Center Completed No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as CT7, MAGE-A3, and WT1 mRNA-electroporated Langerhans cells ( LCs) ClinicalTrials.gov intervention name — accepted as the source's own label NCT01995708 ↗
Modality Cell therapy “autologous Langerhans-type dendritic cells (LCs) electroporated with CT7, MAGE-A3, and Wilms tumor 1 (WT1) messenger RNA (mRNA)” PMID 35100339 ↗ Mar 2022
Route Other “Patients receive CT7/MAGE-A3/WT1 mRNA-electroporated autologous Langerhans-type dendritic cells ID on days 12, 30, and 90 after autologous stem cell transplant.” NCT01995708 ↗