Drugs / CD19CAR-CD28-CD3zeta-EGFRt-expressing Tn/mem-enriched T-lymphocytes
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CD19CAR-CD28-CD3zeta-EGFRt-expressing Tn/mem-enriched T-lymphocytes

Cell therapy targets CD19 via depletion

Developed for
mantle cell lymphoma
Investigated by
City of Hope Medical Center · National Cancer Institute (NCI)

Trials 1 · a red edge is where a trial was stopped

202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT04484012 Dec 2020 → Sep 2026 expected mantle cell lymphoma City of Hope Medical Center Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as CD19CAR-CD28-CD3zeta-EGFRt-expressing Tn/mem-enriched T-lymphocytes ClinicalTrials.gov intervention name — accepted as the source's own label NCT04484012
Action Deplete “These CD19-specific T cells may help the body's immune system identify and kill CD19 positive cancer cells.” NCT04484012
Modality Cell therapy “CD19 chimeric antigen receptor (CAR) T cells” NCT04484012
Route Intravenous “Patients also receive CD19 CAR T cells intravenously (IV) on day 0.” NCT04484012
Target CD19 “recognize CD19NCT04484012