Drugs / Rifaximin-α
last change Jan 2026 re-read 3 minutes ago

Rifaximin-α

also known as rifaximin

Other / unclassified

Developed for
metabolic dysfunction-associated steatotic liver disease · cirrhosis of liver · hepatic encephalopathy
Investigated by
Shanghai Changzheng Hospital

Trials 1

202620272028
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT07381257 Jan 2026 → Dec 2027 expected metabolic dysfunction-associated steatotic liver disease Shanghai Changzheng Hospital Recruiting No outcome recorded
Comparator or background therapy1 trial
Phase 4 NCT02019784 Comparator Jan 2015 → Jun 2016 cirrhosis of liver, hepatic encephalopathy King's College Hospital NHS Trust Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as Rifaximin-α ClinicalTrials.gov intervention name — accepted as the source's own label NCT02019784 ↗
1

NCT07381257 ↗

Known as rifaximin “Rifaximin is a non-absorbable antibiotic that inhibits urease-producing bacteria and reduces absorption of dietary and bacterial ammonia.” PMID 37467180 ↗ Jul 2023
Action Inhibit “inhibits urease-producing bacteria” PMID 37467180 ↗ Jul 2023
Modality Other / unclassified “Rifaximin is a non-absorbable antibiotic” PMID 37467180 ↗ Jul 2023
Route Oral “Rifaximin-α (TARGAXAN TM, manufactured by Alfa-Wasserman, Bologna, Italy) tablets - 550mg twice daily for 90 days” NCT02019784 ↗