Drugs / LY3022855
last change Nov 2020 re-read 9 days ago

LY3022855

also known as IMC-CS4

Monoclonal antibody targets CSF1R via inhibition

Developed for
cancer · melanoma · metastatic neoplasm · neoplasm
Investigated by
Eli Lilly and Company · AstraZeneca · Dana-Farber Cancer Institute

Trials 3

2015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT02718911 Jun 2016 → Dec 2018 cancer Eli Lilly and Company Completed No outcome recorded
Phase 1 NCT02265536 May 2015 → Nov 2017 metastatic neoplasm, neoplasm Eli Lilly and Company Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT03101254 Jun 2017 → Oct 2020 melanoma Dana-Farber Cancer Institute Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as LY3022855 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02265536 ↗
2

NCT03101254 ↗

NCT02718911 ↗

Known as IMC-CS4 “LY3022855 (IMC-CS4)” NCT02265536 ↗
Action Inhibit “CSF-1R inhibitor LY3022855” NCT02718911 ↗
Modality Monoclonal antibody “with the mAb LY3022855.” PMID 32847933 ↗ Aug 2020
Route Intravenous “treated with LY3022855 intravenously” PMID 32847933 ↗ Aug 2020
Target CSF1R “LY3022855 is a colony-stimulating factor-1 receptor (CSF-1R) inhibitor” NCT03101254 ↗