Drugs / BI 891065
last change Dec 2025 re-read 2 minutes ago

BI 891065

Other / unclassified targets BIRC2 via inhibition

Developed for
metastatic neoplasm · neoplasm · non-small cell lung carcinoma
Investigated by
Boehringer Ingelheim

Trials 2 · a red edge is where a trial was stopped

201820192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04138823 Nov 2019 → May 2023 neoplasm Boehringer Ingelheim Completed No outcome recorded
Phase 1 NCT03166631 Sep 2017 → Sep 2020 metastatic neoplasm, non-small cell lung carcinoma Boehringer Ingelheim Terminated No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as BI 891065 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03166631
1

NCT04138823

Action Inhibit “cIAP1 levels were reduced in PBMCs and biopsies” PMID 41408891 Dec 2025
Modality Other / unclassified “BI 891065, a second mitochondria-derived activator of caspases mimetic” PMID 41408891 Dec 2025
Target BIRC2 “targets the inhibitor of apoptosis (IAP) family member cIAP1” PMID 41408891 Dec 2025