Drugs / Elimusertib

Trials 10

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 19 trials
Phase 1 NCT04576091 Jul 2022 → Nov 2024 overdue hypopharynx squamous cell carcinoma, laryngeal squamous cell carcinoma, major salivary gland carcinoma, oropharynx squamous cell carcinoma +3 National Cancer Institute (NCI) Active not recruiting No outcome recorded
Phase 1 NCT05010096 Mar 2022 bone cancer, high grade malignant neoplasm, metastatic malignant neoplasm M.D. Anderson Cancer Center Withdrawn No outcome recorded Stop: Enrollment
Phase 1 NCT04514497 Oct 2021 → Feb 2025 overdue metastatic malignant neoplasm, pancreatic adenocarcinoma, small cell lung carcinoma National Cancer Institute (NCI) Active not recruiting No outcome recorded
Phase 1 NCT04491942 Aug 2021 → Jun 2027 expected bile duct carcinoma, carcinoma of esophagus, cervical carcinoma, endometrial carcinoma +11 National Cancer Institute (NCI) Active not recruiting No outcome recorded
Phase 1 NCT04535401 Aug 2021 → Feb 2025 overdue colorectal carcinoma, gastric carcinoma, gastroesophageal junction adenocarcinoma National Cancer Institute (NCI) Active not recruiting No outcome recorded
Phase 1 NCT04616534 Jun 2021 → Apr 2025 overdue fallopian tube serous adenocarcinoma, ovarian serous adenocarcinoma, pancreatic adenocarcinoma, primary peritoneal serous adenocarcinoma National Cancer Institute (NCI) Active not recruiting No outcome recorded
Phase 1 NCT04267939 Feb 2020 → Dec 2023 ovarian cancer Bayer Terminated No outcome recorded
Phase 1 NCT04095273 Sep 2019 → Nov 2022 cancer Bayer Completed No outcome recorded
Phase 1 NCT03188965 Jul 2017 → Dec 2022 mantle cell lymphoma Bayer Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT05071209 Dec 2021 → Sep 2024 overdue Ewing sarcoma, alveolar rhabdomyosarcoma, lymphoma, refractory malignant neoplasm National Cancer Institute (NCI) Active not recruiting No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 11 sources stand behind the page.

FieldValueCited text
Known as Elimusertib ClinicalTrials.gov intervention name — accepted as the source's own label NCT04616534 ↗
9

NCT04267939 ↗

NCT04535401 ↗

NCT04514497 ↗

NCT04095273 ↗

NCT05010096 ↗

NCT04576091 ↗

NCT05071209 ↗

NCT03188965 ↗

NCT04491942 ↗

Known as BAY1895344 “The purpose of the study is to test how well patients with advanced solid tumors respond to treatment with elimusertib (BAY1895344) in combination with pembrolizumab.” NCT04095273 ↗
2

“Elimusertib (BAY1895344)” NCT04267939 ↗

“Elimusertib (BAY1895344)” NCT03188965 ↗

Known as ELIMUSERTIB (BAY-1895344) ChEMBL registry synonym — accepted as the source's own label CHEMBL4647810 ↗
Action Inhibit “elimusertib, works by blocking a substance (ATR Kinase)” NCT04095273 ↗
Modality Small molecule — CHEMBL4647810 ↗
Route Oral “Solution or tablet, oral, to be administered until evidence of tumor progression” NCT03188965 ↗
Target ATR “blocking a substance (ATR Kinase)” NCT04095273 ↗