Drugs / XO-176
last change Feb 2020 re-read 3 minutes ago

XO-176

also known as FDL176

Small molecule targets CFTR via activation

Developed for
cystic fibrosis
Investigated by
Flatley Discovery Lab LLC

Trials 3

2018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT03516331 Mar → Aug 2018 cystic fibrosis Flatley Discovery Lab LLC Completed No outcome recorded
Phase 1 NCT03173573 Jun 2017 → May 2018 cystic fibrosis Flatley Discovery Lab LLC Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT03756922 Nov 2018 → Feb 2020 cystic fibrosis Flatley Discovery Lab LLC Suspended No outcome recorded Stop: Business

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as XO-176 ChEMBL registry synonym — accepted as the source's own label CHEMBL6068547 ↗
Known as FDL176 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03756922 ↗
2

NCT03516331 ↗

NCT03173573 ↗

Action Activate “CFTR potentiator” NCT03756922 ↗
Modality Small molecule — CHEMBL6068547 ↗
Route Oral “Single and Repeat Oral Doses of FDL176” NCT03173573 ↗
Target CFTR “CFTR corrector and potentiator” NCT03516331 ↗