Drugs / Bulumtatug Fuvedotin
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Bulumtatug Fuvedotin

also known as 9MW2821 · BFv

Monoclonal antibody

Developed for
cancer · cervical cancer · triple-negative breast carcinoma · urothelial carcinoma
Investigated by
Mabwell (Shanghai) Bioscience Co., Ltd.

Trials 4 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT06908928 Aug 2025 → May 2027 expected triple-negative breast carcinoma Mabwell (Shanghai) Bioscience Co., Ltd. Recruiting No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT05216965 Jun 2022 → Dec 2025 cancer Mabwell (Shanghai) Bioscience Co., Ltd. Unknown No outcome recorded
Phase 32 trials
Phase 3 NCT06692166 Sep 2024 → Dec 2027 expected cervical cancer Mabwell (Shanghai) Bioscience Co., Ltd. Recruiting No outcome recorded
Phase 3 NCT06196736 Dec 2023 → Sep 2026 expected urothelial carcinoma Mabwell (Shanghai) Bioscience Co., Ltd. Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as bulumtatug fuvedotin “BACKGROUND: A first-in-human study was carried out to assess the safety and preliminary antitumor activity of bulumtatug fuvedotin (BFv; 9MW2821), a next-generation monoclonal...” PMID 40288679 Apr 2025
1

NCT06908928

Known as 9MW2821 “BACKGROUND: A first-in-human study was carried out to assess the safety and preliminary antitumor activity of bulumtatug fuvedotin (BFv; 9MW2821), a next-generation monoclonal...” PMID 40288679 Apr 2025
1

“An Open-Label, Multicenter, Phase Ib Dose Randomization Study of Bulumtatug Furvedotin (BFv; 9MW2821) in Subjects With Recurrent or Metastatic Triple-Negative Breast Cancer...” NCT06908928

Known as BFv “BACKGROUND: A first-in-human study was carried out to assess the safety and preliminary antitumor activity of bulumtatug fuvedotin (BFv; 9MW2821), a next-generation monoclonal...” PMID 40288679 Apr 2025
1

“An Open-Label, Multicenter, Phase Ib Dose Randomization Study of Bulumtatug Furvedotin (BFv; 9MW2821) in Subjects With Recurrent or Metastatic Triple-Negative Breast Cancer...” NCT06908928

Modality Monoclonal antibody “a next-generation monoclonal antibody-drug conjugate (ADC)” PMID 40288679 Apr 2025
Route Intravenous “receive BFv by intravenous (IV) infusion” PMID 40288679 Apr 2025