Drugs / REP 2139-Mg
last change Nov 2025 re-read 2 minutes ago

REP 2139-Mg

also known as REP

Oligonucleotide (other)

Developed for
chronic hepatitis B virus infection · cirrhosis of liver · hepatitis D virus infection
Investigated by
Replicor Inc.

Trials 1

PhaseRegistry idDatesIndicationSponsorStatusOutcome
NCT05683548 chronic hepatitis B virus infection, cirrhosis of liver, esophageal varices, hepatitis D virus infection +1 Replicor Inc. No longer available No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as REP 2139-Mg ClinicalTrials.gov intervention name — accepted as the source's own label NCT05683548
Known as REP “BACKGROUND & AIMS: REP 2139-Mg (REP), a nucleic acid polymer, blocks HBV subviral particle assembly and HDV replication.” PMID 41205755 Nov 2025
Action Inhibit “blocks HBV subviral particle assembly and HDV replication” PMID 41205755 Nov 2025
Modality Oligonucleotide (other) “BACKGROUND & AIMS: REP 2139-Mg (REP), a nucleic acid polymer, blocks HBV subviral particle assembly and HDV replication.” PMID 41205755 Nov 2025
Route Subcutaneous “once weekly regimen of subcutaneously (SC) administered REP 2139-Mg” NCT05683548