Drugs / R-(-)-gossypol acetic acid
last change Dec 2023 re-read 3 minutes ago

R-(-)-gossypol acetic acid

Developed for
small cell lung carcinoma · adrenal cortex carcinoma · B-cell chronic lymphocytic leukemia · plasma cell myeloma
Investigated by
National Cancer Institute (NCI) · Mayo Clinic

Trials 5

20082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT02697344 Apr 2016 → Oct 2018 plasma cell myeloma Mayo Clinic Completed No outcome recorded
Phase 1 NCT00544596 Sep 2007 → Jul 2013 small cell lung carcinoma National Cancer Institute (NCI) Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT01003769 Jul 2015 → Dec 2018 B-cell chronic lymphocytic leukemia Mayo Clinic Terminated No outcome recorded Stop: Business
Phase 22 trials
Phase 2 NCT00848016 Feb 2009 → Mar 2012 adrenal cortex carcinoma National Cancer Institute (NCI) Completed No outcome recorded
Phase 2 NCT00773955 Nov 2008 → Oct 2009 small cell lung carcinoma National Cancer Institute (NCI) Completed No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as R-(-)-gossypol acetic acid ClinicalTrials.gov intervention name — accepted as the source's own label NCT00773955 ↗
4

NCT00848016 ↗

NCT00544596 ↗

NCT02697344 ↗

NCT01003769 ↗

Action Inhibit “R-(-)-gossypol acetic acid may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth and causing the cells to die.” NCT01003769 ↗
Route Oral “Patients receive oral R-(-)-gossypol twice daily on days 1-3” NCT00544596 ↗