Drugs / incomplete Freund's adjuvant

Trials 11

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 15 trials
Phase 1 NCT04009824 Jul 2019 → Mar 2020 vector-borne disease National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 1 NCT03055000 Feb 2017 → Dec 2018 vector-borne disease National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 1 NCT01585350 Oct 2012 → Jul 2014 melanoma Craig L Slingluff, Jr Completed No outcome recorded
Phase 1 NCT01842139 Dec 2011 → Feb 2015 acute myeloid leukemia with 11q23 abnormalities, acute myeloid leukemia with t(8;21)(q22;q22) translocation, acute myeloid leukemia, del(5q31-q32), acute myeloid leukemia, inv(16)(p13.1;q22) +2 University of Chicago Completed No outcome recorded
Phase 1 NCT00705640 May 2008 → Jun 2009 conjunctival cancer, cutaneous melanoma, ocular melanoma Craig L Slingluff, Jr Completed No outcome recorded
Phase 1/23 trials
Phase 1/2 NCT03617328 Nov 2018 → Jan 2024 melanoma Craig L Slingluff, Jr Completed No outcome recorded
Phase 1/2 NCT00365937 Aug 2006 → Dec 2013 cutaneous melanoma Cliniques universitaires Saint-Luc- Université Catholique de Louvain Terminated No outcome recorded
Phase 1/2 NCT00145158 Jan 2005 → Nov 2007 melanoma Ludwig Institute for Cancer Research Terminated No outcome recorded
Phase 23 trials
Phase 2 NCT00273910 Jan 2006 → May 2010 melanoma National Cancer Institute (NCI) Completed No outcome recorded
Phase 2 NCT00085189 May 2004 → Sep 2007 iris melanoma, medium/large size posterior uveal melanoma, mucosal melanoma, ocular melanoma with extraocular extension +1 University of Southern California Completed No outcome recorded
Phase 2 NCT00012246 Jul 2002 → Jul 2006 bile duct cancer, colorectal cancer, esophageal cancer, gallbladder cancer +3 The University of Texas Medical Branch, Galveston Terminated No outcome recorded
Comparator or background therapy107 trials
Phase 0 NCT01748747 Background Oct 2012 → Dec 2014 melanoma Mayo Clinic Completed No outcome recorded
Phase 0 NCT00640861 Background Aug 2008 → Apr 2015 female breast carcinoma Mayo Clinic Completed No outcome recorded
Phase 0 NCT00091286 Background Mar 2003 → Feb 2008 colorectal cancer Craig L Slingluff, Jr Terminated No outcome recorded Stop: Enrollment
Phase 1 NCT06789198 Background Jul 2025 → Nov 2028 expected fibrolamellar hepatocellular carcinoma University Hospital Tuebingen Recruiting No outcome recorded
Phase 1 NCT05937295 Background Sep 2023 → Sep 2026 overdue fibrolamellar hepatocellular carcinoma University Hospital Tuebingen Recruiting No outcome recorded
Show all 107 trials opens the full record — a long page

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 120 sources stand behind the page.

FieldValueCited text
Known as incomplete Freund's adjuvant ClinicalTrials.gov intervention name — accepted as the source's own label NCT00089063 ↗
50

NCT00109811 ↗

NCT00357461 ↗

NCT00062036 ↗

NCT03879694 ↗

NCT00640861 ↗

NCT00118313 ↗

NCT00077532 ↗

NCT00001703 ↗

NCT00071981 ↗

NCT06202066 ↗

Show 40 more sources

Known as Montanide “Montanide ISA-51 (Incomplete Freund's Adjuvant)” PMID 26500235 ↗ Oct 2015
Known as Montanide ISA 51 VG “Patients will be vaccinated 15 times over 12 months with a vaccine comprised of native and synthetic break-point cluster region-Abelson murine leukemia(BCR-ABL) specific...” NCT00428077 ↗
25

“NY-ESO-1 recombinant protein (250 µg) was mixed with Poly-ICLC (1 mg) and Montanide ISA-51 VG (1 mL) and administered SC directly following the ipilimumab infusion every 3...” NCT01810016 ↗

“Will receive an admixture of the wildtype and epitope enhanced TARP peptides emulsified with Montanide ISA 51 VG and granulocyte-macrophage colony-stimulating factor (GM-CSF).” NCT00972309 ↗

“FusionVAC-22 peptide will be administered subcutaneously (s.c.) with the TLR1/2 ligand XS15 (50 µg) emulsified in Montanide ISA 51 VG (1:1).” NCT06789198 ↗

“Peptides will be administered subcutaneously (s.c.) together with the TLR1/2 ligand XS15 emulsified in Montanide ISA 51 VG as adjuvant” NCT05014607 ↗

“P10s-PADRE vaccine combined with MONTANIDE™ ISA 51 VG "Chemotherapy" Subcutaneous injection” NCT02264236 ↗

“the Toll-like receptor 1/2 ligand XS15 (50 μg) emulsified in Montanide ISA 51 VG (1:1).” NCT05937295 ↗

“NY-ESO-1 recombinant protein mixed with CpG 7909 and Montanide ISA-51 VG” NCT00299728 ↗

“P16_37-63 peptide combined with Montanide® ISA-51 VG” NCT02526316 ↗

“P10s-PADRE/MONTANIDE ISA 51 VG vaccine” NCT03003195 ↗

“mixed with 0.3 ml Montanide ISA-51 VG” NCT01462838 ↗

Show 15 more sources

Known as Montanide ISA-51 “Arm 1, vaccine alone: patients received i.d. injections of Melan-A: 26-35 (A27L) and gp100: 209-217 (210M) peptides (250 µg each) formulated in Montanide ISA-51 plus s.c....” NCT00559026 ↗
43

“Participants were randomly assigned (1:1:1), using block randomisation and a computer-generated randomisation sequence, to treatment with either 200 nmol of AGS-v vaccine...” PMID 32534628 ↗ Jun 2020

“PD-L1 peptide (100 micrograms) emulsified with the adjuvant Montanide ISA-51 given subcutaneously 10 times every second week over the course of 26 weeks including a five-week break.” NCT03850522 ↗

“Montanide ISA™ 51 is a water-in-oil (W/O) emulsion composed of a mineral oil and a surfactant from the mannide monooleate family with immune stimulatory effect .” NCT06218511 ↗

“CDCA1,URLC10,KIF20A,DEPDC1 and MPHOSPH1 peptides (0.5, 1 or 2mg of each peptide) mixed with Montanide ISA 51 will be administered by subcutaneous injection.” NCT01259505 ↗

“PEP-CMV Component A mixed with Montanide ISA-51 (1:1 volume ratio) intradermally administered half in the RIGHT groin and half in the LEFT groin.” NCT03299309 ↗

“URLC10-117 peptide(1mg), VEGFR1 peptide(1mg) and VEGFR2 peptide(1mg) mixed with Montanide ISA 51 will be administered by subcutaneous injection.” NCT00681421 ↗

“Subcutaneous injection in the upper arm with 500mcg of FLU-v as 0.5ml emulsion in 0.25ml of WFI and 0.25ml of adjuvant Montanide ISA-51” NCT03180801 ↗

“Patients receive carcinoembryonic antigen peptide 1-6D (CAP 1-6D) emulsified in Montanide ISA-51 adjuvant subcutaneously on day 1.” NCT00012246 ↗

“100 micrograms (mcg) granulocyte-macrophage colony-stimulating factor (GM-CSF) and 1 milliliter (mL) of Montanide ISA-51 adjuvant.” NCT05479045 ↗

“On each vaccination day, the URLC10 peptide (1mg) mixed with Montanide ISA 51 will be administered by endodermic injection” NCT00753844 ↗

Show 33 more sources

Known as Montanide(R) ISA-51 “a synthetic CpG 7909 ODN (deoxycytidyl-deoxyguanosin oligodeoxy-nucleotides) mixed with NY-ESO-1 peptide p157-165 and incomplete Freund's adjuvants (Montanide(R) ISA-51) led to...” PMID 19728336 ↗ Feb 2010
Modality Other / unclassified “incomplete Freund's adjuvant” NCT00003339 ↗
Route Subcutaneous “injected subcutaneously every four weeks” NCT00001703 ↗