Drugs / CC-90009
last change Apr 2024 re-read 2 minutes ago

CC-90009

Other / unclassified targets GSPT1

Developed for
acute myeloid leukemia · myelodysplastic syndrome
Investigated by
Celgene Corporation · AbbVie

Trials 3 · a red edge is where a trial was stopped

2017201820192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04336982 Aug 2020 → Oct 2023 acute myeloid leukemia Celgene Corporation Terminated No outcome recorded
Phase 1 NCT04297124 Mar 2020 → Jun 2021 Celgene Corporation Completed No outcome recorded
Phase 1 NCT02848001 Nov 2016 → Apr 2023 acute myeloid leukemia, myelodysplastic syndrome Celgene Corporation Terminated No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as CC-90009 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02848001
2

NCT04297124

NCT04336982

Modality Other / unclassified “first-in-class GSPT1-selective cereblon E3 ligase modulator, CC-90009” PMID 33197925 Feb 2021
Route Intravenous “Will be administered intravenously per dosing schedule in a 28-day cycle” NCT02848001
Target GSPT1 “selectively target GSPT1 for ubiquitination and proteasomal degradation” PMID 33197925 Feb 2021