Drugs / PSMA-TTC
last change Oct 2024 re-read 9 days ago

PSMA-TTC

also known as BAY 2315497
Developed for
prostate carcinoma
Investigated by
Bayer

Trials 1

20192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT03724747 Dec 2018 → Aug 2022 prostate carcinoma Bayer Completed No outcome recorded

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2021-04-06 Bayer Results Bayer to present new clinical data in indolent non-Hodgkin’s Lymphoma and additional research on its oncology portfolio at AACR Annual Meeting 2021 bayer.com ↗
A featured presentation will highlight the PSMA-TTC BAY 2315497, targeting prostate specific membrane antigen (PSMA) in prostate cancer cells, showing synergistic anti-tumor activity in combination with PARP inhibitor olaparib in preclinical prostate cancer models.

Evidence & citations 2 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as PSMA-TTC “We describe a novel, antibody-based TAT, the PSMA-targeted thorium-227 conjugate PSMA-TTC (BAY 2315497) consisting of the alpha-particle emitter thorium-227 complexed by a...” PMID 31831560 ↗ Dec 2019
Known as BAY 2315497 “We describe a novel, antibody-based TAT, the PSMA-targeted thorium-227 conjugate PSMA-TTC (BAY 2315497) consisting of the alpha-particle emitter thorium-227 complexed by a...” PMID 31831560 ↗ Dec 2019