drugset
Drugs / Bromazepam
last change Jun 2025 re-read 2 minutes ago

Bromazepam

also known as Bromazepam civ · Lectopam · Lexatin · Lexotan · lexotanil · NSC-140669 · RO 5-3350

Small molecule targets GABRA2 via activation

Developed for
depressive disorder · schizophrenia · anxiety · bipolar disorder · personality disorder · post-traumatic stress disorder
Investigated by
Hannover Medical School · Rakitzi, Stavroula

Trials 2 · a red edge is where a trial was stopped

today NCT06993662 · Ph 1 NCT02374567 · Ph 3
20152016201720182019202020212022202320242025202620272028
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT06993662 Jun 2025 → Dec 2027 expected anxiety, bipolar disorder, depressive disorder, obsessive-compulsive disorder +3 Rakitzi, Stavroula Active not recruiting No outcome recorded
Phase 31 trial
Phase 3 NCT02374567 Jan 2015 → Jun 2017 anxiety disorder, dementia, depressive disorder, schizophrenia +1 Hannover Medical School Terminated No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 4 NCT04410536 Background Jun 2020 → Dec 2021 migraine disorder Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta Completed No outcome recorded

Evidence & citations 12 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as Bromazepam “bromazepam 1.5 mg, 1 tablet after breakfast, lunch and dinner for every day” NCT04410536 ↗
1

NCT02374567 ↗
Known as Bromazepam civ ChEMBL registry synonym — accepted as the source's own label CHEMBL277062 ↗
Known as Lectopam ChEMBL registry synonym — accepted as the source's own label CHEMBL277062 ↗
Known as Lexatin ChEMBL registry synonym — accepted as the source's own label CHEMBL277062 ↗
Known as Lexotan ChEMBL registry synonym — accepted as the source's own label CHEMBL277062 ↗
Known as lexotanil “The combination of pharmacotherapy (anxiolytics (Tavor, clonotril, lexotanil), antidepressants (SSRI, SNRI)) and individual cognitive behavioral psychotherapy by anxiety...” NCT06993662 ↗
Known as NSC-140669 ChEMBL registry synonym — accepted as the source's own label CHEMBL277062 ↗
Known as RO 5-3350 ChEMBL registry synonym — accepted as the source's own label CHEMBL277062 ↗
Action Activate “GABA receptor alpha-2 subunit positive allosteric modulator” CHEMBL277062 ↗
Modality Small molecule — CHEMBL277062 ↗
Route Oral “oral administration of a bridge therapy to reduce the withdrawal symptoms and rebound headache (prednisone 25 mg , 2 tablets after breakfast for 5 days, one tablet for 3 days,...” NCT04410536 ↗
Target GABRA2 “GABA receptor alpha-2 subunit positive allosteric modulator” CHEMBL277062 ↗