Drugs / ERGOLOID
ERGOLOID
also known as
Ergoloid Mesylates · Alkergot · Circanol · Co-dergocrine mesilate · Deapril · Deapril-st · Dihydroergotoxine mesilate · Dihydroergotoxine mesylate · +7 more
Regulatory milestones approvals, filings & regulatory actions · 2 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Label expansion | US (FDA) | HYDERGINE | — | 1975-06-02 | fda.gov ↗ |
| Approved | US (FDA) | HYDERGINE | — | 1953-11-05 | fda.gov ↗ |
Trials 1 · a red edge is where a trial was stopped
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| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 2 | NCT05030129 | Oct 2021 → Jan 2023 | fragile X syndrome | Elizabeth Berry-Kravis | Completed | No outcome recorded |
Also used as a comparator or background therapy in 1 trial
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 2 | NCT01475578 Comparator | Mar → Oct 2002 | vascular dementia | Sinphar Pharmaceutical Co., Ltd | Completed | No outcome recorded |
Evidence & citations 20 cited values
Every value below carries the sentence it was read from. 3 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | ERGOLOID | ChEMBL registry synonym — accepted as the source's own label CHEMBL2364968 ↗ |
| Known as | Alkergot | ChEMBL registry synonym — accepted as the source's own label CHEMBL2364968 ↗ |
| Known as | Circanol | ChEMBL registry synonym — accepted as the source's own label CHEMBL2364968 ↗ |
| Known as | Co-dergocrine mesilate | ChEMBL registry synonym — accepted as the source's own label CHEMBL2364968 ↗ |
| Known as | Deapril | ChEMBL registry synonym — accepted as the source's own label CHEMBL2364968 ↗ |
| Known as | Deapril-st | ChEMBL registry synonym — accepted as the source's own label CHEMBL2364968 ↗ |
| Known as | Dihydroergotoxine mesilate | ChEMBL registry synonym — accepted as the source's own label CHEMBL2364968 ↗ |
| Known as | Dihydroergotoxine mesylate | ChEMBL registry synonym — accepted as the source's own label CHEMBL2364968 ↗ |
| Known as | Dihydroergotoxine methanesulfonate | ChEMBL registry synonym — accepted as the source's own label CHEMBL2364968 ↗ |
| Known as | Dihydrogenated ergot alkaloids | ChEMBL registry synonym — accepted as the source's own label CHEMBL2364968 ↗ |
| Known as | Ergoloid mesilates | ChEMBL registry synonym — accepted as the source's own label CHEMBL2364968 ↗ |
| Known as | Ergoloid Mesylates | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01475578 ↗ |
| Known as | Gerimal | ChEMBL registry synonym — accepted as the source's own label CHEMBL2364968 ↗ |
| Known as | Hydergine | ChEMBL registry synonym — accepted as the source's own label CHEMBL2364968 ↗ |
| Known as | Hydergine lc | ChEMBL registry synonym — accepted as the source's own label CHEMBL2364968 ↗ |
| Known as | Hydrogenated ergot alkaloids | ChEMBL registry synonym — accepted as the source's own label CHEMBL2364968 ↗ |
| Action | Activate | “Serotonin 1b (5-HT1b) receptor agonist” CHEMBL2364968 ↗1“Serotonin 1a (5-HT1a) receptor agonist” CHEMBL2364968 ↗ |
| Route | Oral | “Ergoloid Mesylates tablet (manufactured by Tianjin Huajin Pharmaceutical Factory; Batch number: 011230), 2 tablets/time, 3 times/day, orally before meal” NCT01475578 ↗ |
| Target | HTR1A | “Serotonin 1a (5-HT1a) receptor agonist” CHEMBL2364968 ↗ |
| Target | HTR1B | “Serotonin 1b (5-HT1b) receptor agonist” CHEMBL2364968 ↗ |