Drugs / deulorlatinib
last change Oct 2025 re-read 3 minutes ago

deulorlatinib

also known as TGRX-326

targets ALK, ROS1 via inhibition

Developed for
non-small cell lung carcinoma
Investigated by
Shenzhen TargetRx Co., Ltd. · Sun Yat-sen University Cancer Center

Trials 1

20222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT05441956 Apr 2021 → Aug 2025 overdue non-small cell lung carcinoma Shenzhen TargetRx Co., Ltd. Active not recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as deulorlatinib “Safety, Efficacy, and Biomarker Analysis of Deulorlatinib (TGRX-326) in Anaplastic Lymphoma Kinase-Positive NSCLC: A Multicenter, Open-Label, Phase 1/1b Trial.” PMID 39551469 ↗ Nov 2024
Known as TGRX-326 “Safety, Efficacy, and Biomarker Analysis of Deulorlatinib (TGRX-326) in Anaplastic Lymphoma Kinase-Positive NSCLC: A Multicenter, Open-Label, Phase 1/1b Trial.” PMID 39551469 ↗ Nov 2024
Action Inhibit “Deulorlatinib is a highly brain-penetrant, new-generation ALK/ROS1 inhibitor.” PMID 39551469 ↗ Nov 2024
Target ALK “Deulorlatinib is a highly brain-penetrant, new-generation ALK/ROS1 inhibitor.” PMID 39551469 ↗ Nov 2024
Target ROS1 “Deulorlatinib is a highly brain-penetrant, new-generation ALK/ROS1 inhibitor.” PMID 39551469 ↗ Nov 2024