Drugs / E8001
last change Aug 2023 re-read 3 minutes ago

E8001

Small interfering RNA (siRNA) targets C5 via inhibition

Investigated by
Eisai Inc.

Trials 1

202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04609852 Oct 2020 → Aug 2023 — Eisai Inc. Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as E8001 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04609852 ↗
Action Inhibit “C5 siRNA-LNP completely suppressed C5 expression” PMID 35749284 ↗ Nov 2022
Modality Small interfering RNA (siRNA) “a lipid nanoparticle (LNP) formulation of small-interfering RNA against complement C5 (C5 siRNA-LNP)” PMID 35749284 ↗ Nov 2022
Route Intravenous “Intravenous infusion.” NCT04609852 ↗
Target C5 “small-interfering RNA against complement C5 (C5 siRNA-LNP)” PMID 35749284 ↗ Nov 2022