Drugs / GLPG2737
last change Apr 2023 re-read 3 minutes ago

GLPG2737

also known as ABBV 2737 · G-1117337

Small molecule

Developed for
cystic fibrosis · autosomal dominant polycystic kidney disease
Investigated by
Lakefront Biotherapeutics NV

Trials 6

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 14 trials
Phase 1 NCT03540524 May 2018 → Mar 2019 cystic fibrosis Lakefront Biotherapeutics NV Completed No outcome recorded
Phase 1 NCT03450720 Jun → Aug 2017 cystic fibrosis Lakefront Biotherapeutics NV Completed No outcome recorded
Phase 1 NCT03128606 Mar 2017 → Feb 2018 — Lakefront Biotherapeutics NV Completed No outcome recorded
Phase 1 NCT03410979 Nov 2016 → Aug 2017 — Lakefront Biotherapeutics NV Completed No outcome recorded
Phase 22 trials · 1 met primary · 1 missed
Phase 2 NCT04578548 Nov 2020 → Dec 2022 autosomal dominant polycystic kidney disease Lakefront Biotherapeutics NV Terminated Missed primary
Phase 2 NCT03474042 Nov 2017 → Apr 2018 cystic fibrosis Lakefront Biotherapeutics NV Completed Met primary

News releases announcing trial results or a regulatory action · 2

DateIssuerRelease
2018-06-28 Lakefront Biotherapeutics NV Results Topline results of PELICAN trial and update on triple combo development plans lakefrontbio.com ↗
GLPG2737 achieved primary efficacy endpoint and was well-tolerated in patients
2017-06-20 Lakefront Biotherapeutics NV Results Galapagos’ R&D Update 2017: rapidly advancing our product candidates lakefrontbio.com ↗
Galapagos reports that Phase 1 results on GLPG2451, GLPG2222 and GLPG2737 showed favorable findings relating to safety and tolerability of the individual components that constitute our current most advanced potential triple combination therapy.

All press releases naming this drug 3 releases

DateIssuerRelease

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as GLPG2737 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04578548 ↗
5

NCT03450720 ↗

NCT03410979 ↗

NCT03474042 ↗

NCT03540524 ↗

NCT03128606 ↗

Known as ABBV 2737 ChEMBL registry synonym — accepted as the source's own label CHEMBL6068548 ↗
Known as G-1117337 ChEMBL registry synonym — accepted as the source's own label CHEMBL6068548 ↗
Modality Small molecule — CHEMBL6068548 ↗
Route Oral “GLPG3067 oral tablet, GLPG2222 oral tablet and GLPG2737 oral capsule, multiple doses, daily for 14 days” NCT03128606 ↗