Drugs / O-CHLOROACETYLCARBAMOYLFUMAGILLOL
last change May 2004 re-read 3 minutes ago

O-CHLOROACETYLCARBAMOYLFUMAGILLOL

also known as TNP-470 · AGM-1470 · NSC-642492

Small molecule

Developed for
HIV infectious disease · Kaposi's sarcoma · pancreatic neoplasm
Investigated by
M.D. Anderson Cancer Center · National Institute of Allergy and Infectious Diseases (NIAID)

Trials 2

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00000763 ? → Feb 1997 HIV infectious disease, Kaposi's sarcoma National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 21 trial
Phase 2 NCT00038701 Aug 1999 → May 2004 pancreatic neoplasm M.D. Anderson Cancer Center Terminated No outcome recorded Stop: Enrollment

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as O-CHLOROACETYLCARBAMOYLFUMAGILLOL ChEMBL registry synonym — accepted as the source's own label CHEMBL424278 ↗
Known as AGM-1470 ChEMBL registry synonym — accepted as the source's own label CHEMBL424278 ↗
Known as NSC-642492 ChEMBL registry synonym — accepted as the source's own label CHEMBL424278 ↗
Known as TNP-470 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00038701 ↗
1

NCT00000763 ↗

Action Inhibit “drugs that inhibit angiogenesis, such as TNP-470, may be of benefit in patients with the disease.” NCT00000763 ↗
Modality Small molecule — CHEMBL424278 ↗
Route Intravenous “intravenous TNP-470” NCT00000763 ↗