Drugs / trabodenoson
last change May 2017 re-read 2 minutes ago

trabodenoson

also known as INO-8875 · INNO-8875 · PJ-875

Small molecule targets ADORA1 via activation

Developed for
ocular hypertension · open-angle glaucoma · glaucoma
Investigated by
Inotek Pharmaceuticals Corporation

Trials 5 · a red edge is where a trial was stopped

201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT01123772 May 2010 → Feb 2011 Inotek Pharmaceuticals Corporation Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT01123785 May 2010 → Dec 2011 glaucoma, ocular hypertension Inotek Pharmaceuticals Corporation Completed No outcome recorded
Phase 22 trials
Phase 2 NCT02829996 Aug 2016 → May 2017 ocular hypertension, open-angle glaucoma Inotek Pharmaceuticals Corporation Completed No outcome recorded
Phase 2 NCT01917383 Aug 2013 → Aug 2014 ocular hypertension, open-angle glaucoma Inotek Pharmaceuticals Corporation Completed No outcome recorded
Phase 31 trial
Phase 3 NCT02565173 Sep 2015 → Nov 2016 ocular hypertension, open-angle glaucoma Inotek Pharmaceuticals Corporation Completed No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as trabodenoson ClinicalTrials.gov intervention name — accepted as the source's own label NCT02565173
2

NCT01917383

NCT02829996

Known as INNO-8875 ChEMBL registry synonym — accepted as the source's own label CHEMBL3545407
Known as INO-8875 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01123772
1

NCT01123785

Known as PJ-875 ChEMBL registry synonym — accepted as the source's own label CHEMBL3545407
Action Activate “Adenosine A1 receptor agonist” CHEMBL3545407
1

“Adenosine agonist eye drop” NCT01123785

Modality Small molecule CHEMBL3545407
Route Topical Topical Ocular Application of INO-8875” NCT01123772
Target ADORA1 “Adenosine A1 receptor agonist” CHEMBL3545407