Drugs / VX-135
last change Jun 2014 re-read 2 minutes ago

VX-135

Small molecule

Developed for
chronic hepatitis C virus infection
Investigated by
Vertex Pharmaceuticals Incorporated · Alios Biopharma Inc.

Trials 3 · a red edge is where a trial was stopped

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT01842451 Jun 2013 → May 2014 chronic hepatitis C virus infection Vertex Pharmaceuticals Incorporated Completed No outcome recorded
Phase 2 NCT01790100 Feb 2013 → Jun 2014 chronic hepatitis C virus infection Alios Biopharma Inc. Completed No outcome recorded
Phase 2 NCT01726946 Nov 2012 → Feb 2014 chronic hepatitis C virus infection Vertex Pharmaceuticals Incorporated Completed No outcome recorded

Press releases naming this drug 7 releases

DateIssuerRelease
2014-01-09 Vertex Pharmaceuticals Incorporated Vertex Announces Sustained Viral Response Rate (SVR4) Data from All-Oral Study of VX-135 in Combination with Daclatasvir in Hepatitis C vrtx.com
2013-07-25 Vertex Pharmaceuticals Incorporated Vertex Provides Update on Ongoing All-Oral Studies of VX-135 in Hepatitis C vrtx.com
2013-04-23 Vertex Pharmaceuticals Incorporated ALS-2200 (VX-135) Viral Kinetic Study Shows Significant Reduction in HCV RNA in People with Genotype 1 Hepatitis C Virus Infection and Cirrhosis, and in People with Genotypes 2, 3 or 4 HCV Infection vrtx.com
2013-04-05 Vertex Pharmaceuticals Incorporated Vertex Enters Agreement with Bristol-Myers Squibb for Phase 2 All-Oral Studies of VX-135 in Combination with Daclatasvir for the Treatment of Hepatitis C vrtx.com
2012-11-10 Vertex Pharmaceuticals Incorporated Data from Viral Kinetic Study Showed Rapid Reduction of HCV RNA with ALS-2200 (VX-135), Vertex's Oral Nucleotide Analogue in Development for the Treatment of Hepatitis C vrtx.com
2012-11-01 Vertex Pharmaceuticals Incorporated Vertex Enters Agreement with GlaxoSmithKline for Phase 2 All-Oral Study of VX-135 and GSK2336805 for the Treatment of Hepatitis C vrtx.com
2012-11-01 Vertex Pharmaceuticals Incorporated Vertex Announces Collaboration with Janssen To Initiate Phase 2 All-Oral Study of VX-135 and Simeprevir (TMC435) for the Treatment of Hepatitis C vrtx.com

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as VX-135 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01726946
2

NCT01790100

NCT01842451

Modality Small molecule CHEMBL4783446
Route Oral orally administered VX-135 with ribavirin” NCT01790100