Drugs / TRIGONELLAMIDE
TRIGONELLAMIDE
also known as
TRIA-662 · 1-methylnicotinamide Chloride · 1-MNA · N-methylnicotinamide Chloride · Trigonellinamide
Trials 3
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 12 trials | ||||||
| Phase 1 | NCT01809301 | Mar → May 2013 | — | Cortria Corporation | Completed | No outcome recorded |
| Phase 1 | NCT01930240 | Nov 2007 → Jan 2008 | — | Cortria Corporation | Completed | No outcome recorded |
| Phase 21 trial | ||||||
| Phase 2 | NCT02008084 | Dec 2013 → Oct 2015 | hyperlipidemia, combined, 2, hypertriglyceridemia | Cortria Corporation | Completed | No outcome recorded |
| Comparator or background therapy2 trials | ||||||
| Phase 1 | NCT00685737 Comparator | Dec 2007 → Jun 2008 | hyperlipidemia | Pharmena North America | Completed | No outcome recorded |
| Phase 2/3 | NCT00758303 Comparator | Sep 2007 → Dec 2008 | hyperlipidemia | Cortria Corporation | Completed | No outcome recorded |
Evidence & citations 8 cited values
Every value below carries the sentence it was read from. 6 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | TRIGONELLAMIDE | ChEMBL registry synonym — accepted as the source's own label CHEMBL71733 ↗ |
| Known as | 1-methylnicotinamide Chloride | “The objective of this study is to compare the absorption of a niacin metabolite (1-methylnicotinamide, 1-MNA) from TRIA-662 (1-methylnicotinamide chloride)relative to the...” NCT01809301 ↗1“A Randomized, Double-blind, Placebo-controlled, Forced Dose-escalation, Multi-center Pilot Study to Evaluate the Lipid Regulating Effects of TRIA-662 (1-methylnicotinamide Chloride)” NCT02008084 ↗ |
| Known as | 1-MNA | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00685737 ↗ |
| Known as | N-methylnicotinamide Chloride | “The primary objective of the study is to assess the blood profile of the N-methylnicotinamide (MNA) following administration of TRIA-662 (N-methylnicotinamide Chloride).” NCT01930240 ↗ |
| Known as | TRIA-662 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01930240 ↗ |
| Known as | Trigonellinamide | ChEMBL registry synonym — accepted as the source's own label CHEMBL71733 ↗ |
| Modality | Small molecule | — CHEMBL71733 ↗ |
| Route | Oral | “Oral Dosages of 1-MNA” NCT00685737 ↗ |