Drugs / Imeglimin
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Imeglimin

also known as EMD-387008 · Imeglimina · Imeglimine · Twymeeg

Small molecule

Developed for
type 2 diabetes mellitus
Investigated by
Poxel SA · Mansoura University · National Center for Global Health and Medicine, Japan · Sumitomo Pharma Co., Ltd.

Trials 7 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 14 trials
Phase 1 NCT03802786 Nov 2018 → Jul 2019 Poxel SA Completed No outcome recorded
Phase 1 NCT03618316 Jun → Jul 2018 Poxel SA Completed No outcome recorded
Phase 1 NCT02924337 Sep → Dec 2016 PR interval, variation in Poxel SA Completed No outcome recorded
Phase 1 NCT02373150 Feb → Oct 2015 type 2 diabetes mellitus Poxel SA Completed No outcome recorded
Phase 21 trial
Phase 2 NCT01951235 Jan 2013 → Jul 2014 type 2 diabetes mellitus Poxel SA Completed No outcome recorded
Phase 42 trials
Phase 4 NCT07436182 Mar → Jun 2026 overdue Mansoura University Not yet recruiting No outcome recorded
Phase 4 NCT05366868 May 2022 → Aug 2026 overdue type 2 diabetes mellitus National Center for Global Health and Medicine, Japan Active not recruiting No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 8 sources stand behind the page.

FieldValueCited text
Known as Imeglimin ClinicalTrials.gov intervention name — accepted as the source's own label NCT03618316
6

NCT03802786

NCT07436182

NCT02373150

NCT02924337

NCT05366868

NCT01951235

Known as EMD-387008 ChEMBL registry synonym — accepted as the source's own label CHEMBL4297514
Known as Imeglimina ChEMBL registry synonym — accepted as the source's own label CHEMBL4297514
Known as Imeglimine ChEMBL registry synonym — accepted as the source's own label CHEMBL4297514
Known as Twymeeg “Imeglimin (Twymeeg)” NCT07436182
Action Activate “enhances mitochondrial Complex I and III activity” NCT07436182
Modality Small molecule CHEMBL4297514
Route Oral “Tablet, oral, single dose” NCT02924337