Drugs / VH3810109
last change May 2026 re-read 2 minutes ago

VH3810109

also known as GSK3810109 · N6LS
Developed for
HIV infectious disease
Investigated by
ViiV Healthcare

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT07053384 Jul 2025 → Jan 2027 expected HIV infectious disease ViiV Healthcare Active not recruiting No outcome recorded
Phase 1 NCT05291520 Feb 2022 → Apr 2023 HIV infectious disease ViiV Healthcare Completed No outcome recorded
Phase 21 trial
Phase 2 NCT05996471 Aug 2023 → May 2026 overdue HIV infectious disease ViiV Healthcare Active not recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as VH3810109 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05996471
2

NCT05291520

NCT07053384

Known as GSK3810109 “Safety and pharmacokinetics of a single dose of VH3810109 (also known as GSK3810109), administered either subcutaneously (SC) with rHuPH20 or intravenously (IV)” NCT05291520
1

“single dose of VH3810109 (also known as GSK3810109), administered either subcutaneously” PMID 40698814 Jul 2025

Known as N6LS “The CD4-binding site antibody VH3810109 (N6LS) demonstrated broad and potent neutralization activity in vitro and robust antiviral activity in people with HIV-1.” PMID 40698814 Jul 2025
Route Subcutaneous “Participants in this group received a single subcutaneous (SC) dose of VH3810109 20 mg/kg co-administered with rHuPH20 at Day 1 and were followed up to 24 weeks.” NCT05291520