Drugs / Cedirogant
last change Jan 2024 re-read 3 minutes ago

Cedirogant

also known as ABBV-157 · ABV-157

Small molecule targets RORC

Developed for
psoriasis
Investigated by
AbbVie

Trials 3

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT05376839 Jul → Nov 2022 — AbbVie Terminated No outcome recorded Stop: Business
Phase 1 NCT03922607 Jun 2019 → Apr 2021 psoriasis AbbVie Completed No outcome recorded
Phase 21 trial
Phase 2 NCT05044234 Nov 2021 → Nov 2022 psoriasis AbbVie Terminated No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as Cedirogant “Cedirogant (ABBV-157) is an orally bioavailable inverse agonist of retinoic acid-related orphan receptor gamma thymus.” PMID 38231873 ↗ Jan 2024
2

NCT05044234 ↗

NCT05376839 ↗

Known as ABBV-157 “Cedirogant (ABBV-157) is an orally bioavailable inverse agonist of retinoic acid-related orphan receptor gamma thymus.” PMID 38231873 ↗ Jan 2024
1

“Multiple Doses of Cedirogant (ABBV-157) in Subjects” NCT05376839 ↗

Known as ABV-157 ChEMBL registry synonym — accepted as the source's own label CHEMBL5095174 ↗
Modality Small molecule — CHEMBL5095174 ↗
Route Oral “ABBV-157 will be administered orally as capsule” NCT03922607 ↗
Target RORC “Cedirogant (ABBV-157) is an orally bioavailable inverse agonist of retinoic acid-related orphan receptor gamma thymus.” PMID 38231873 ↗ Jan 2024