Drugs / EX-527
last change Dec 2023 re-read 3 minutes ago

EX-527

also known as Selisistat

Small molecule targets SIRT1 via inhibition

Developed for
endometriosis · female infertility

Trials 0

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Comparator or background therapy1 trial
Phase 2 NCT04184323 Comparator Jan 2022 → Dec 2023 endometriosis, female infertility Wake Forest University Health Sciences Withdrawn No outcome recorded Stop: Business

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as EX-527 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04184323 ↗
Known as Selisistat “EX-527 (Selisistat)” NCT04184323 ↗
Action Inhibit “EX-527 is a specific inhibitor of the histone deacetylase Sirtuin-1 (SirT1).” NCT04184323 ↗
Modality Small molecule “investigate a small molecule inhibitor of SirT1” NCT04184323 ↗
Target SIRT1 “EX-527 is a specific inhibitor of the histone deacetylase Sirtuin-1 (SirT1).” NCT04184323 ↗