Drugs / MTX-463
last change Mar 2026 re-read 3 minutes ago

MTX-463

Monoclonal antibody targets CCN4

Developed for
idiopathic pulmonary fibrosis
Investigated by
Mediar Therapeutics · ICON plc

Trials 3

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT07450521 Feb → Mar 2026 — Mediar Therapeutics Completed No outcome recorded
Phase 1 NCT06401213 Apr → Nov 2024 — Mediar Therapeutics Completed No outcome recorded
Phase 21 trial
Phase 2 NCT06967805 May 2025 → Aug 2027 expected idiopathic pulmonary fibrosis Mediar Therapeutics Recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as MTX-463 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07450521 ↗
2

NCT06967805 ↗

NCT06401213 ↗

Modality Monoclonal antibody “immunoglobin G1 (IgG1) monoclonal antibody” NCT06401213 ↗
Route Intravenous “by intravenous (IV) infusion” NCT06967805 ↗
Target WISP1 “directed against WNT-inducible signaling pathway protein 1 (WISP1)” NCT06401213 ↗