Drugs / Selective Antigen Specific dTβRII-expressing T cells
last change Jan 2026 re-read 2 minutes ago

Selective Antigen Specific dTβRII-expressing T cells

Cell therapy

Developed for
Ewing sarcoma · neuroblastoma · rhabdomyosarcoma · Wilms tumor
Investigated by
Cancer Research UK · Children's National Research Institute · National Cancer Institute (NCI) · The Mark Foundation for Cancer Research

Trials 1 · a red edge is where a trial was stopped

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT07172958 Jan 2026 → Dec 2035 expected Ewing sarcoma, Wilms tumor, neuroblastoma, rhabdomyosarcoma Children's National Research Institute Recruiting No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as Selective Antigen Specific dTβRII-expressing T cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT07172958
Modality Cell therapy “DNR-TA T cells and B7-H3 CAR T cells will be generated and combined into a final product comprised of the two T cell components combined at a 1:1 ratio.” NCT07172958
Route Intravenous “followed by intravenous infusion of the combined CAR-TA T cell product.” NCT07172958