Drugs / Peg-IFN

Trials 7

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 23 trials · 1 met primary
Phase 2 NCT07069569 Jun 2025 → Jul 2027 expected chronic hepatitis B virus infection Ausper Biopharma Co., Ltd. Recruiting No outcome recorded
Phase 2 NCT04676724 Jan 2021 → Feb 2023 chronic hepatitis B virus infection GlaxoSmithKline Completed No outcome recorded
Phase 2 NCT04225715 Jul 2020 → Jul 2024 chronic hepatitis B virus infection Hoffmann-La Roche Completed Met primary
Phase 31 trial
Phase 3 NCT01625338 Jun 2012 → Oct 2014 chronic hepatitis C virus infection Gilead Sciences Completed No outcome recorded
Phase 43 trials
Phase 4 NCT01938781 Jun 2013 → Dec 2016 fibrotic liver disease Beijing Friendship Hospital Completed No outcome recorded
Phase 4 NCT01743521 Jan 2013 → Nov 2015 chronic hepatitis C virus infection Kirby Institute Completed No outcome recorded
Phase 4 NCT00979706 Mar 2005 → Nov 2014 HIV infectious disease Juan A. Arnaiz Completed No outcome recorded
Comparator or background therapy9 trials
Phase 1 NCT01582035 Background Apr 2012 → Nov 2013 hepatitis C virus infection Janssen R&D Ireland Completed No outcome recorded
Phase 2 NCT00983060 Background Sep 2009 → Apr 2011 — Novartis Pharmaceuticals Completed No outcome recorded
Phase 2 NCT00774397 Comparator Oct 2008 → Nov 2011 chronic hepatitis C virus infection Boehringer Ingelheim Completed Met primary
Phase 3 NCT01608737 Comparator Sep 2012 → Oct 2015 chronic hepatitis C virus infection Boehringer Ingelheim Withdrawn No outcome recorded
Phase 3 NCT01405560 Background Sep 2011 → Mar 2013 chronic hepatitis C virus infection Merck Sharp & Dohme LLC Completed No outcome recorded

Press releases naming this drug 11 releases

DateIssuerRelease
2024-06-06 Gilead Sciences Gilead Announces New England Journal of Medicine Publication of Data that Demonstrate Bulevirtide with PegIFN Achieved Post-Treatment Undetectable HDV RNA gilead.com ↗
2021-04-23 Zydus Lifesciences Limited Zydus receives Emergency Use Approval from DCGI for the use of Pegylated Interferon alpha-2b, Virafin in treating moderate COVID-19 infection in adults zyduslife.com ↗
2021-04-05 Zydus Lifesciences Limited Zydus seeks DCGI approval for the use of Pegylated Interferon alpha-2b in treating COVID-19 zyduslife.com ↗
2013-11-02 Boehringer Ingelheim Phase 3 data show viral cure rates achieved in a broad range of patients with genotype-1 hepatitis C taking investigational compound faldaprevir plus PegIFN/RBV prnewswire.com ↗
2012-04-19 Gilead Sciences Gilead Announces Sustained Virologic Response Data for 12-Week Regimen of GS-7977 Plus Pegylated Interferon and Ribavirin in Genotype 1 Hepatitis C Patients gilead.com ↗
2011-09-04 Gilead Sciences Gilead Amends Study Design for Ongoing Hepatitis C Clinical Trials That Include GS 9190, Pegylated Interferon and Ribavirin, and Another Direct-Acting Antiviral Agent gilead.com ↗
2010-10-30 Boehringer Ingelheim Results of Boehringer Ingelheim Oral Hepatitis C Protease Inhibitor and Polymerase Inhibitor Combination Phase Ib Trial Shows Rapid Viral Response Without Use of Pegylated Interferon prnewswire.com ↗
2008-04-24 Vertex Pharmaceuticals Incorporated Vertex Announces Positive Interim Results with Telaprevir-based Therapy in Genotype 1 Chronic Hepatitis C Patients who Failed to Achieve SVR with Previous Pegylated Interferon & Ribavirin Treatment vrtx.com ↗
2006-05-21 Vertex Pharmaceuticals Incorporated Researchers Report Results for 28-day Phase II Study of VX-950 in Combination with Pegylated Interferon and Ribavirin in Hepatitis C Patients vrtx.com ↗
2006-04-29 Vertex Pharmaceuticals Incorporated Researchers Report Initial Results for 14-day Phase Ib Study of VX-950, and Pegylated Interferon, Showing Anti-HCV Activity in Combination in Hepatitis C Patients vrtx.com ↗
2006-01-09 Vertex Pharmaceuticals Incorporated VX-950, Investigational Oral Hepatitis C Protease Inhibitor, Demonstrates Rapid and Dramatic Reduction in Viral Levels in Combination with Pegylated Interferon vrtx.com ↗

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 16 sources stand behind the page.

FieldValueCited text
Known as Peg IFN “BID in various doses (between 100 mg - 600 mg bid) + SOC (PEG IFN and RBV)” NCT00983060 ↗
16

“pegylated interferon alfa (Peg IFN)(180ug subcutaneous once weekly)” NCT01582035 ↗

“PegIFN is to be injected once per week for 24 or 48 weeks.” NCT01582035 ↗

NCT01330316 ↗

NCT01625338 ↗

NCT00979706 ↗

NCT01938781 ↗

NCT01405560 ↗

NCT01370642 ↗

NCT00774397 ↗

NCT04676724 ↗

Show 6 more sources

Known as pegylated interferon “Pegylated Interferon (PegIFN) and ribavirin (RBV)” NCT01330316 ↗
1

“pegylated interferon (Peg-IFN)” NCT01625338 ↗

Known as pegylated interferon alfa “pegylated interferon alfa (Peg IFN)(180ug subcutaneous once weekly)” NCT01582035 ↗
Known as pegylated-interferon a2b “weekly sc pegylated-interferon a2b (Peg-INF)(1.5 mcg/kg/week)” NCT00979706 ↗
Modality Protein / enzyme biologic “Biological: Peg-IFN” NCT01370642 ↗
Route Subcutaneous “weekly sc pegylated-interferon a2b” NCT00979706 ↗