Drugs / TBAJ-876
last change Jul 2026 re-read 2 minutes ago

TBAJ-876

also known as sorfequiline

Small molecule

Developed for
pulmonary tuberculosis
Investigated by
Global Alliance for TB Drug Development

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT05526911 Jun → Sep 2022 lung disorder, multidrug-resistant tuberculosis, pulmonary tuberculosis Global Alliance for TB Drug Development Completed No outcome recorded
Phase 22 trials
Phase 2 NCT07672405 Jul 2026 → May 2027 expected pulmonary tuberculosis Global Alliance for TB Drug Development Recruiting No outcome recorded
Phase 2 NCT06058299 Oct 2023 → Dec 2024 overdue pulmonary tuberculosis Global Alliance for TB Drug Development Active not recruiting No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04493671 Comparator Jun 2020 → Jun 2022 lung disorder, multidrug-resistant tuberculosis, pulmonary tuberculosis Global Alliance for TB Drug Development Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as TBAJ-876 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05526911
1

NCT04493671

Known as sorfequiline ClinicalTrials.gov intervention name — accepted as the source's own label NCT06058299
1

NCT07672405

Modality Small molecule “TBAJ-876, a second-generation diarylquinoline with greater antimycobacterial activity” PMID 39194204 Aug 2024
Route Oral “TBAJ-876 oral suspension, orally administered” NCT04493671