Drugs / TNG456
last change Mar 2025 re-read 2 minutes ago

TNG456

targets PRMT5 via inhibition

Developed for
glioblastoma · non-small cell lung carcinoma
Investigated by
Eli Lilly and Company · Tango Therapeutics, Inc.

Trials 1 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT06810544 Mar 2025 → Mar 2027 expected brain neoplasm, glioblastoma, lung adenocarcinoma Tango Therapeutics, Inc. Recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as TNG456 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06810544
Action Inhibit “The study drug, TNG456, is a selective PRMT5 inhibitor administered orally.” NCT06810544
Route Oral “administered orally” NCT06810544
Target PRMT5 “The study drug, TNG456, is a selective PRMT5 inhibitor administered orally.” NCT06810544