Drugs / zalfermin

Trials 11 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 19 trials
Phase 1 NCT07087795 Jul 2025 → Sep 2026 expected type 1 diabetes mellitus Novo Nordisk A/S Active not recruiting No outcome recorded
Phase 1 NCT06188026 Dec 2023 → Dec 2024 Novo Nordisk A/S Completed No outcome recorded
Phase 1 NCT05917938 Jul 2023 → Dec 2024 Novo Nordisk A/S Completed No outcome recorded
Phase 1 NCT05766709 Mar 2023 → Jan 2024 metabolic dysfunction-associated steatohepatitis Novo Nordisk A/S Completed No outcome recorded
Phase 1 NCT05742919 Feb → Jun 2023 NAFLD1 Novo Nordisk A/S Completed No outcome recorded
Phase 1 NCT05727644 Feb → Nov 2023 metabolic dysfunction-associated steatohepatitis Novo Nordisk A/S Completed No outcome recorded
Phase 1 NCT04722653 Feb → Apr 2021 metabolic dysfunction-associated steatohepatitis Novo Nordisk A/S Completed No outcome recorded
Phase 1 NCT03479892 Mar 2018 → Jun 2019 metabolic disease, obesity disorder Novo Nordisk A/S Completed No outcome recorded
Phase 1 NCT03015207 Jan → Oct 2017 metabolic disease, obesity disorder Novo Nordisk A/S Completed No outcome recorded
Phase 22 trials
Phase 2 NCT06409130 May 2024 → Nov 2025 alcoholic liver disease Novo Nordisk A/S Completed No outcome recorded
Phase 2 NCT05016882 Aug 2021 → Dec 2024 metabolic dysfunction-associated steatohepatitis Novo Nordisk A/S Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 13 sources stand behind the page.

FieldValueCited text
Known as zalfermin “This first-in-human study investigated the safety, pharmacokinetics, and pharmacodynamics of the long-acting fibroblast growth factor 21 (FGF21) analog zalfermin.” PMID 41351276 Dec 2025
Known as NN-9499 ChEMBL registry synonym — accepted as the source's own label CHEMBL5314897
Known as NNC0194-0499 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06188026
10

NCT06409130

NCT05742919

NCT05766709

NCT07087795

NCT05016882

NCT03479892

NCT05727644

NCT04722653

NCT03015207

NCT05917938

Known as Zalfermina ChEMBL registry synonym — accepted as the source's own label CHEMBL5314897
Known as Zalfermine ChEMBL registry synonym — accepted as the source's own label CHEMBL5314897
Modality Protein / enzyme biologic “long-acting fibroblast growth factor 21 (FGF21) analog” PMID 41351276 Dec 2025
Route Subcutaneous subcutaneous zalfermin” PMID 41351276 Dec 2025