Drugs / Radium-1 TCR
last change Apr 2024 re-read 3 minutes ago

Radium-1 TCR

Cell therapy

Developed for
colorectal cancer
Investigated by
Oslo University Hospital

Trials 1

2018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT03431311 Mar 2018 → Jun 2019 colorectal cancer Oslo University Hospital Terminated No outcome recorded Stop: Business

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as Radium-1 TCR “Following 12 escalating doses of autologous T cells electroporated with in-vitro-transcribed Radium-1 TCR mRNA” PMID 38582964 ↗ Apr 2024
Action Deplete “We confirmed cytotoxicity of transfected Radium-1 T cells against target cells” PMID 38582964 ↗ Apr 2024
Modality Cell therapy “The patients will be given adoptive cell therapy (ACT) with Radium-1 TCR+ T cells” NCT03431311 ↗
Route Intravenous “The ACT will be administered as two intravenous (i.v.) injections of GMP TCR T cells per week for 6 weeks.” NCT03431311 ↗