Drugs / autologous activated platelet-rich plasma
last change Dec 2021 re-read 2 minutes ago

autologous activated platelet-rich plasma

also known as aaPRP · PRP

targets TNF via inhibition

Developed for
acute respiratory distress syndrome · COVID-19
Investigated by
Hayandra Peduli Foundation · Koja Regional Public Hospital

Trials 1 · a red edge is where a trial was stopped

202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT04715360 Dec 2020 → Nov 2021 COVID-19, acute respiratory distress syndrome Hayandra Peduli Foundation Unknown No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as autologous activated platelet-rich plasma ClinicalTrials.gov intervention name — accepted as the source's own label NCT04715360
Known as aaPRP “In this study, we aimed to evaluate the potential of autologous activated platelet-rich plasma (aaPRP) and the outcomes for treating severe Coronavirus Disease-2019 (COVID-19)...” NCT04715360
Known as PRP “activated platelet-rich plasma (PRP) produces anti-inflammatory effects in inflammatory condition that is beneficial for tissue regeneration.” NCT04715360
Action Inhibit “PRP decreases IL-1β, IL-6, IL-8, and TNFα inflammatory genes expression while also reduces IL-1β and TNFα inflammatory cytokines production.” NCT04715360
Route Other “autologous activated platelet-rich plasma transfusion” NCT04715360
Target TNF “PRP decreases IL-1β, IL-6, IL-8, and TNFα inflammatory genes expression while also reduces IL-1β and TNFα inflammatory cytokines production.” NCT04715360