Drugs / ASP8477
last change Feb 2015 re-read 3 minutes ago

ASP8477

Small molecule targets CYP2C19 via inhibition

Developed for
diabetic polyneuropathy · neuropathy, painful · postherpetic neuralgia
Investigated by
Astellas Pharma Europe B.V.

Trials 1

20112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT02220777 Nov 2010 → May 2011 — Astellas Pharma Europe B.V. Completed No outcome recorded
Comparator or background therapy1 trial
Phase 2 NCT02065349 Comparator Feb 2014 → Feb 2015 diabetic polyneuropathy, neuropathy, painful, postherpetic neuralgia Astellas Pharma Europe B.V. Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as ASP8477 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02065349 ↗
1

NCT02220777 ↗

Action Inhibit “ASP8477 is known to have the strongest inhibitory effect on CYP2C19.” NCT02220777 ↗
Modality Small molecule — CHEMBL5095212 ↗
Route Oral “oral” NCT02065349 ↗
Target CYP2C19 “ASP8477 is known to have the strongest inhibitory effect on CYP2C19.” NCT02220777 ↗