Drugs / GSK249320
last change Jul 2014 re-read 3 minutes ago

GSK249320

Monoclonal antibody targets MAG via inhibition

Developed for
transient ischemic attack · cerebral infarction
Investigated by
GlaxoSmithKline

Trials 1

201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT00833989 Jul 2009 → Jan 2011 transient ischemic attack GlaxoSmithKline Completed No outcome recorded
Comparator or background therapy1 trial
Phase 2 NCT01808261 Comparator May 2013 → Jul 2014 cerebral infarction GlaxoSmithKline Terminated No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as GSK249320 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00833989 ↗
1

NCT01808261 ↗

Action Inhibit “antagonises or neutralises MAG-mediated inhibition” NCT00833989 ↗
Modality Monoclonal antibody “GSK249320 is a humanised monoclonal antibody (mAb)” NCT00833989 ↗
Route Intravenous “I.V. infusion” NCT00833989 ↗
Target MAG “binds with high specificity to myelin-associated glycoprotein (MAG)” NCT00833989 ↗