Drugs / Lemzoparlimab
last change Apr 2024 re-read 2 minutes ago

Lemzoparlimab

also known as TJ011133

Monoclonal antibody

Developed for
myelodysplastic syndrome · acute myeloid leukemia · cancer · lymphoma · neoplasm · plasma cell myeloma
Investigated by
TJ Biopharma Co., Ltd. · AbbVie · I-Mab Biopharma US Limited · Merck Sharp & Dohme LLC

Trials 6 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT04895410 Jan → Jun 2022 plasma cell myeloma AbbVie Terminated No outcome recorded
Phase 1 NCT04912063 Jun 2021 → May 2023 acute myeloid leukemia, myelodysplastic syndrome AbbVie Terminated No outcome recorded
Phase 1 NCT03934814 Apr 2019 → Jan 2023 cancer, lymphoma I-Mab Biopharma US Limited Completed No outcome recorded
Phase 1/22 trials
Phase 1/2 NCT05148533 Dec 2021 → Feb 2023 neoplasm TJ Biopharma Co., Ltd. Terminated No outcome recorded
Phase 1/2 NCT04202003 Mar 2020 → Dec 2023 acute myeloid leukemia, myelodysplastic syndrome TJ Biopharma Co., Ltd. Completed No outcome recorded
Phase 31 trial
Phase 3 NCT05709093 Mar 2023 → Apr 2024 myelodysplastic syndrome TJ Biopharma Co., Ltd. Terminated No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as Lemzoparlimab ClinicalTrials.gov intervention name — accepted as the source's own label NCT04895410
2

NCT05709093

NCT04912063

Known as TJ011133 TJ011133 (30 mg/kg, 45 mg/kg, QW) in combination with toripalimab injection (240 mg, Q3W).” NCT05148533
2

NCT03934814

NCT04202003

Modality Monoclonal antibody CHEMBL4650520
Route Intravenous Intravenous (IV) infusion” NCT04895410