Drugs / DS-8895a
last change Aug 2019 re-read 3 minutes ago

DS-8895a

Monoclonal antibody targets EPHA2

Developed for
cancer
Investigated by
Daiichi Sankyo · Austin Health · Ludwig Institute for Cancer Research

Trials 2

20142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT02252211 Dec 2014 → Sep 2016 cancer Ludwig Institute for Cancer Research Completed No outcome recorded
Phase 1 NCT02004717 Oct 2013 → Feb 2017 cancer Daiichi Sankyo Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as DS-8895a ClinicalTrials.gov intervention name — accepted as the source's own label NCT02252211 ↗
1

NCT02004717 ↗

Modality Monoclonal antibody “DS-8895a is a humanized anti-EPHA2 IgG1 monoclonal antibody afucosylated to enhance antibody-dependent cellular cytotoxicity activity.” PMID 31412935 ↗ Aug 2019
Route Intravenous “DS-8895a was intravenously administered every 2 weeks for the duration of the study, with a 28-day period to assess dose-limiting toxicity (DLT).” PMID 31412935 ↗ Aug 2019
Target EPHA2 “DS-8895a is a humanized anti-EPHA2 IgG1 monoclonal antibody afucosylated to enhance antibody-dependent cellular cytotoxicity activity.” PMID 31412935 ↗ Aug 2019