Drugs / Ozone
Ozone
Trials 19
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 23 trials | ||||||
| Phase 2 | NCT05853523 | Feb 2021 → Feb 2022 | dentin sensitivity | University of L'Aquila | Completed | No outcome recorded |
| Phase 2 | NCT04789135 | Mar → Sep 2020 | interstitial cystitis | Anhembi Morumbi University | Unknown | No outcome recorded |
| Phase 2 | NCT00946634 | Jan → Mar 2009 | periapical periodontitis | University of Sao Paulo | Completed | No outcome recorded |
| Phase 2/35 trials | ||||||
| Phase 2/3 | NCT06799351 | Feb 2025 → Dec 2029 expected | chemotherapy-induced neuropathy | Bernardino Clavo, MD, PhD | Recruiting | No outcome recorded |
| Phase 2/3 | NCT06706544 | Feb 2025 → Dec 2029 expected | chemotherapy-induced neuropathy | Bernardino Clavo, MD, PhD | Recruiting | No outcome recorded |
| Phase 2/3 | NCT04299893 | Nov 2020 → Sep 2027 expected | chemotherapy-induced neuropathy, neurological pain disorder, neuropathy, painful | Bernardino Clavo, MD, PhD | Recruiting | No outcome recorded |
| Phase 2/3 | NCT03660657 | Feb → Nov 2020 | ischemic disease | Bernardino Clavo, MD, PhD | Terminated | No outcome recorded Stop: Enrollment |
| Phase 2/3 | NCT03876067 | Apr 2019 → Mar 2022 | ischemic disease | Assiut University | Unknown | No outcome recorded |
| Phase 34 trials | ||||||
| Phase 3 | NCT06802354 | Dec 2024 → Dec 2025 | impacted teeth, multiple | Jelena Krunic | Completed | No outcome recorded |
| Phase 3 | NCT05689996 | Jan → Apr 2023 | keratitis | Assiut University | Unknown | No outcome recorded |
| Phase 3 | NCT04426721 | Jun 2020 → Dec 2021 | osteoarthritis, knee | Humanitas Clinical and Research Center | Unknown | No outcome recorded |
| Phase 3 | NCT04370223 | May → Oct 2020 | pneumonia | Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta | Unknown | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT05304884 | Jun 2021 → Feb 2022 | — | Erzurum Regional Training & Research Hospital | Completed | No outcome recorded |
| Phase not applicable6 trials | ||||||
| — | NCT07498998 | Jul → Aug 2026 overdue | carpal tunnel syndrome | Tanta University | Not yet recruiting | No outcome recorded |
| — | NCT06130618 | Sep 2023 → Mar 2024 | piriformis syndrome | Ankara City Hospital Bilkent | Unknown | No outcome recorded |
| — | NCT05875506 | May → Aug 2023 | alveolar periostitis, bone inflammation disease | Minia University | Completed | No outcome recorded |
| — | NCT06909305 | Oct 2022 → Oct 2023 | osteoarthritis, knee | Tanta University | Completed | No outcome recorded |
| — | NCT04420572 | Mar → Jun 2021 | — | Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey | Completed | No outcome recorded |
| — | NCT06900907 | Mar → Aug 2017 | impacted teeth, multiple | Batman University | Completed | No outcome recorded |
| Comparator or background therapy7 trials | ||||||
| Phase 2 | NCT00566007 Comparator | Dec 2008 → Mar 2014 | lumbar disk disease | Kovacs Foundation | Terminated | No outcome recorded |
| Phase 4 | NCT02910765 Comparator | Oct 2016 → Mar 2017 | infectious disease with sepsis | Assiut University | Unknown | No outcome recorded |
| — | NCT06133712 Comparator | Nov 2023 → Dec 2025 overdue | carpal tunnel syndrome | Tanta University | Recruiting | No outcome recorded |
| — | NCT05318560 Comparator | Jun → Sep 2022 | myofascial pain syndrome | Pamukkale University | Unknown | No outcome recorded |
| — | NCT05837494 Comparator | Jun 2022 → May 2023 | osteoarthritis, knee | Tanta University | Completed | No outcome recorded |
| — | NCT05000463 Comparator | Feb → Aug 2022 | chronic pain syndrome | Assiut University | Unknown | No outcome recorded |
| — | NCT03742466 Comparator | Nov 2018 → Jul 2019 | carpal tunnel syndrome, chronic pain syndrome, scleroderma | Assiut University | Completed | No outcome recorded |
Evidence & citations 8 cited values
Every value below carries the sentence it was read from. 27 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | ozone | “Ozone injection” NCT06130618 ↗ |
| Known as | Aqueous Ozone | “Drug: Aqueous Ozone” NCT00946634 ↗ |
| Known as | Gas ozone | “Combination Product: Gas ozone” NCT05853523 ↗ |
| Known as | Ozone-Based Agent | “Drug: Ozone-Based Agent” NCT05689996 ↗ |
| Known as | Triatomic oxygen | ChEMBL registry synonym — accepted as the source's own label CHEMBL2447938 ↗ |
| Action | Inhibit | “At low doses, O3 reduces the synthesis of prostaglandins (PGS) by inhibiting prostaglandin endoperoxide synthase (PGHS2) and cyclooxygenase (COXs).” NCT04789135 ↗ |
| Modality | Other / unclassified | “local ozone therapy” NCT03742466 ↗ |
| Route | Other | “Infiltration of intradiscal ozone” NCT00566007 ↗ |