Drugs / TYRA-300
last change Jun 2025 re-read 3 minutes ago

TYRA-300

targets FGFR3 via inhibition

Developed for
non-invasive bladder urothelial carcinoma · achondroplasia
Investigated by
Tyra Biosciences, Inc

Trials 3

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT05544552 Nov 2022 → Nov 2026 expected non-invasive bladder urothelial carcinoma Tyra Biosciences, Inc Active not recruiting No outcome recorded
Phase 22 trials
Phase 2 NCT06995677 Jun 2025 → Feb 2028 expected non-invasive bladder urothelial carcinoma Tyra Biosciences, Inc Recruiting No outcome recorded
Phase 2 NCT06842355 Mar 2025 → Jan 2030 expected achondroplasia Tyra Biosciences, Inc Recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as TYRA-300 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05544552 ↗
2

NCT06842355 ↗

NCT06995677 ↗

Action Inhibit “a novel, potent fibroblast growth factor receptor (FGFR) 3-selective tyrosine kinase inhibitor” NCT05544552 ↗
Route Oral “TYRA-300 is an oral” NCT05544552 ↗
Target FGFR3 “a novel, potent fibroblast growth factor receptor (FGFR) 3-selective tyrosine kinase inhibitor” NCT05544552 ↗