Drugs / RINUCUMAB
last change Apr 2017 re-read 2 minutes ago

RINUCUMAB

also known as REGN2176

Monoclonal antibody targets PDGFRB via inhibition

Developed for
wet macular degeneration
Investigated by
Regeneron Pharmaceuticals

Trials 1 · a red edge is where a trial was stopped

201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT02418754 May 2015 → Aug 2016 wet macular degeneration Regeneron Pharmaceuticals Terminated No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as RINUCUMAB ChEMBL registry synonym — accepted as the source's own label CHEMBL3545316
Known as REGN2176 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02418754
Action Inhibit “Platelet-derived growth factor receptor beta inhibitor” CHEMBL3545316
Modality Monoclonal antibody CHEMBL3545316
Route Intravitreal Intravitreal injection of REGN2176-3 (REGN2176 1 mg and REGN3 2 mg) every 4 weeks for 12 weeks.” NCT02418754
Target PDGFRB “Platelet-derived growth factor receptor beta inhibitor” CHEMBL3545316