Drugs / VOB560
last change Mar 2026 re-read 2 minutes ago

VOB560

also known as S65487

Small molecule targets BCL2 via inhibition

Developed for
acute myeloid leukemia · B-cell chronic lymphocytic leukemia · non-Hodgkin lymphoma · plasma cell myeloma · refractory plasma cell neoplasm
Investigated by
ADIR, a Servier Group company · Servier · Novartis Pharmaceuticals

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT04702425 Jun 2021 → Jul 2024 acute myeloid leukemia, non-Hodgkin lymphoma, plasma cell myeloma Novartis Pharmaceuticals Terminated No outcome recorded
Phase 1 NCT03755154 Jul 2019 → Nov 2023 B-cell chronic lymphocytic leukemia, acute myeloid leukemia, refractory plasma cell neoplasm Servier Terminated No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT04742101 Mar 2021 → Mar 2026 acute myeloid leukemia Servier Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as VOB560 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04702425
Known as S65487 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03755154
1

NCT04742101

Action Inhibit “a Bcl-2 Inhibitor” NCT03755154
Modality Small molecule CHEMBL3701382
Route Intravenous “administered intravenously” NCT03755154
Target BCL2 “S65487, a Bcl-2 Inhibitor” NCT03755154