Drugs / Interferon Alfacon-1

Regulatory milestones approvals, filings & regulatory actions · 2 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Withdrawn EU (EMA) Infergen 2006-05-05 europa.eu
Approved EU (EMA) Infergen 1999-02-01 europa.eu

Trials 9 · a red edge is where a trial was stopped

19992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027202820292030
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT02464007 Jan 2016 → Nov 2024 neoplastic disease or syndrome Sichuan Huiyang Life Science and Technology Corporation Terminated No outcome recorded
Phase 1 NCT02387307 Jul 2013 → Jun 2018 colon carcinoma, hepatocellular carcinoma, melanoma, non-small cell lung carcinoma +1 Sichuan Huiyang Life Science and Technology Corporation Completed No outcome recorded
Phase 22 trials
Phase 2 NCT07662278 Jan 2027 → Jan 2030 expected Sichuan Huiyang Life Science and Technology Corporation Not yet recruiting No outcome recorded
Phase 2 NCT05485584 Jul 2022 → Apr 2023 COVID-19 Sichuan Huiyang Life Science and Technology Corporation Completed No outcome recorded
Phase 33 trials
Phase 3 NCT00162734 Feb 2005 → Jun 2007 chronic hepatitis C virus infection Bausch Health Americas, Inc. Completed No outcome recorded
Phase 3 NCT00086541 Jun 2004 → Jan 2007 chronic hepatitis C virus infection Bausch Health Americas, Inc. Completed No outcome recorded
Phase 3 NCT00239252 hepatitis C virus infection Astellas Pharma Inc Completed No outcome recorded
Phase 42 trials
Phase 4 NCT00456248 Feb → Oct 2007 chronic hepatitis C virus infection Kadmon Corporation, LLC Terminated No outcome recorded
Phase 4 NCT00266318 Dec 2005 → May 2007 hepatitis C virus infection Beth Israel Medical Center Completed No outcome recorded
Also used as a comparator or background therapy in 3 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT01227798 Comparator Nov 2010 → Nov 2011 influenza University Health Network, Toronto Unknown No outcome recorded
Phase 31 trial
Phase 3 NCT00211692 Comparator Jul 2005 → Jul 2008 chronic hepatitis C virus infection Minneapolis Veterans Affairs Medical Center Completed No outcome recorded
Phase 41 trial
Phase 4 NCT00207402 Background Oct 2005 → Jan 2010 hepatitis C virus infection Brooke Army Medical Center Completed No outcome recorded

Evidence & citations 13 cited values

Every value below carries the sentence it was read from. 13 sources stand behind the page.

FieldValueCited text
Known as Interferon Alfacon-1 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00086541
5

NCT00266318

NCT00211692

NCT01227798

NCT00239252

NCT00162734

Known as CIFN “Daily Infergen (Interferon Alfacon-1, CIFN) (9 or 15 µg) + Ribavirin (1000-1200 mg, based on body weight) PO Daily for up to 48 wks” NCT00086541
3

“Daily Infergen (Interferon Alfacon-1, CIFN) (9 or 15 µg) + Ribavirin (1000-1200 mg, based on body weight) PO Daily for up to 48 wks” NCT00162734

“consensus interferon (CIFN, CIFN or interferon alfacon-1) has greater antiviral activity in vitro” NCT00211692

“daily interferon alfacon-1 (Infergen, CIFN) at high dosage (24 mcg)” NCT00266318

Known as consensus interferon Consensus interferon for chronic hepatitis C patients with genotype 1 who failed to respond to, or relapsed after, interferon alpha-2b and ribavirin in combination: an Italian...” PMID 11984144 May 2002
1

consensus interferon (CIFN, CIFN or interferon alfacon-1) has greater antiviral activity in vitro” NCT00211692

Known as IFN-alphacon1 “The Interferon-alpha (also called Interferon-alphacon1 or IFN-alphacon1 or INFERGEN) is an immune molecule” NCT01227798
Known as Infergen “Daily Infergen (Interferon Alfacon-1, CIFN) (9 or 15 µg) + Ribavirin (1000-1200 mg, based on body weight) PO Daily for up to 48 wks” NCT00086541
5

“Daily Infergen (Interferon Alfacon-1, CIFN) (9 or 15 µg) + Ribavirin (1000-1200 mg, based on body weight) PO Daily for up to 48 wks” NCT00162734

“The Interferon-alpha (also called Interferon-alphacon1 or IFN-alphacon1 or INFERGEN) is an immune molecule” NCT01227798

“daily interferon alfacon-1 (Infergen, CIFN) at high dosage (24 mcg)” NCT00266318

Infergen (interferon alfacon-1)” NCT00207402

NCT00456248

Known as Infergen (interferon alfacon-1) Infergen (interferon alfacon-1)NCT00207402
Known as Interferon-alpha “The Interferon-alpha (also called Interferon-alphacon1 or IFN-alphacon1 or INFERGEN) is an immune molecule” NCT01227798
Known as Interferon-alphacon1 “The Interferon-alpha (also called Interferon-alphacon1 or IFN-alphacon1 or INFERGEN) is an immune molecule” NCT01227798
Known as Recombinant Super-compound Interferon Recombinant Super-compound Interferon (rSIFN-co)” NCT05485584
1

NCT07662278

Known as Recombinant-Compound Interferon (rSIFN-co) Recombinant-Compound Interferon (rSIFN-co)NCT02387307
Known as rSIFN-co “Recombinant Super-Compound Interferon (rSIFN-co)” NCT07662278
3

NCT05485584

NCT02464007

NCT02387307

Modality Protein / enzyme biologic “The Interferon-alpha (also called Interferon-alphacon1 or IFN-alphacon1 or INFERGEN) is an immune molecule” NCT01227798
Route Subcutaneous “daily CIFN (15 mcg/day SQ)” NCT00211692