Drugs / VRC-HIVMAB060-00-AB
Trials 3
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 13 trials | ||||||
| Phase 1 | NCT02471326 | Jul 2015 → Apr 2017 | HIV infectious disease | National Institute of Allergy and Infectious Diseases (NIAID) | Completed | No outcome recorded |
| Phase 1 | NCT01993706 | Nov 2013 → Feb 2015 | HIV infectious disease | National Institute of Allergy and Infectious Diseases (NIAID) | Completed | No outcome recorded |
| Phase 1 | NCT01950325 | Aug 2013 → Aug 2015 | HIV infectious disease | National Institute of Allergy and Infectious Diseases (NIAID) | Completed | No outcome recorded |
| Comparator or background therapy1 trial | ||||||
| Phase 1 | NCT03831945 Comparator | Apr 2019 → Dec 2020 | HIV infectious disease | National Institute of Allergy and Infectious Diseases (NIAID) | Terminated | No outcome recorded Stop: Enrollment |
Evidence & citations 6 cited values
Every value below carries the sentence it was read from. 6 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | VRC-HIVMAB060-00-AB | ClinicalTrials.gov intervention name — accepted as the source's own label NCT03831945 ↗ |
| Known as | VRC01 | “VRC-HIVMAB060-00-AB (VRC01) is a broadly neutralizing HIV-1 monoclonal antibody (mAb) isolated from the B cells of an HIV-infected patient.” PMID 26332605 ↗ Sep 20152“This is the first clinical trial of the VRC-HIVMAB060-00-AB (VRC01) monoclonal antibody.” NCT01950325 ↗ “VRC-HIVMAB060-00-AB (VRC01)” NCT02471326 ↗ |
| Action | Inhibit | “In summary, a single infusion of mAb VRC01 significantly decreased plasma viremia and preferentially suppressed neutralization-sensitive virus strains.” PMID 26702094 ↗ Dec 2015 |
| Modality | Monoclonal antibody | “VRC01 Human Monoclonal Antibody” NCT01950325 ↗ |
| Route | Intravenous | “Administered intravenously or subcutaneously to HIV-Infected Adults” NCT01950325 ↗ |
| Route | Subcutaneous | “Administered intravenously or subcutaneously to HIV-Infected Adults” NCT01950325 ↗ |