Drugs / MTX-474
last change Apr 2026 re-read 3 minutes ago

MTX-474

Monoclonal antibody

Developed for
diffuse cutaneous systemic sclerosis
Investigated by
Mediar Therapeutics

Trials 2

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT06535841 Jul 2024 → Apr 2025 — Mediar Therapeutics Completed No outcome recorded
Phase 21 trial
Phase 2 NCT07287670 Apr 2026 → Dec 2028 expected diffuse cutaneous systemic sclerosis Mediar Therapeutics Recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as MTX-474 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07287670 ↗
1

NCT06535841 ↗

Action Inhibit “has demonstrated ability to block phosphorylation” NCT06535841 ↗
Modality Monoclonal antibody “immunoglobin G1 (IgG1) monoclonal antibody” NCT06535841 ↗
Route Intravenous “receive MTX-474 or a matching placebo by intravenous (IV) infusion” NCT07287670 ↗